09:30 – 10:50
SESSION I - TRANSCRIPTION CONTRIBUTION TO GENOME STABILITY
Chair: Tibor Pankotai
09:30 – 9:50
Acute RNA polymerase II perturbation by arsenic triggers arm-wide γH2A signaling
Ireneusz Litwin
09:50 – 10:10
IDO1 driven metabolic and transcriptional programs inhibit migration and growth in breast cancer
Zsolt Rádul
10:10 – 10:30
Structural basis for senataxin roles in R-loop resolution and transcription termination
Marek Sebesta
10:30 – 10:50
Functional interplay between Dbl2 and Hst4 in replication-associated transcriptional control
Veronika Novysedláková
10:50 – 11:20
Coffee break
11:20 – 13:00
SESSION II - CHROMATIN DYNAMICS AND GENOME STRUCTURE
Chair: Silvia Bagelova Polakova
11:20 – 11:40
DNA clamp dynamics in the maintenance of genome stability in Arabidopsis thaliana
Martina Nešpor Dadejová
11:40 – 12:00
Epigenetic priming with valeric acid unlocks multi-stress resistance in plants by targeted histone deacetylase inhibition
Marta Koblowska
12:00 – 12:20
PBRM1 deficiency shifts the cellular response to LRP1 silencing from apoptosis to perturbed cell-cycle progression
Katarzyna Arczewska
12:20 – 12:40
Stability and changeability of genome structures in yeast species
Matthias Sipiczki
12:40 – 13:00
Revisiting the molecular mechanisms of gene targeting: Insights from the ends-out paradigm
Petar Tomev Mitrikeski
14:00 – 15:40
SESSION III - MOLECULAR RESPONSES TO STRESSES
Chair: Dávid Szüts
14:00 – 14:20
K63-linked ubiquitylation of S2P-RNAPII regulates transcription in a DNAPK inter-dependent manner in response to double-strand breaks
Tibor Pankotai
14:20 – 14:40
PolySUMOylation - a way to control ubiquitination at replication stress sites
Karol Kramarz
14:40 - 15:00
Involvement of the yeast PARP (Pyl1) in the resolution of replication stress on dysfunctional telomeres
Regina Sepšiová
15:00 – 15:20
Cell size and genome stability as dynamic determinants of the reproductive potential of yeast cells
Renata Zadrąg-Tęcza
15:20 – 15:40
Non-catalytic subunits of the CMGE complex - implications for genome stability
Michał Dmowski
15:40 – 16:10
Coffee break
16:10 – 17:50
SESSION IV - MUTAGENESIS AND GENOME INSTABILITY
Chair: Justyna McIntyre
16:10 – 16:30
Is an altered replicative lifespan always determined by the condition of genomic DNA?
Adrianna Skoneczna
16:30 – 16:50
The mutagenic role of human DNA polymerase iota in spontaneous and hypoxia-induced mutagenesis
Bilal Ahmad Seh
16:50 – 17:10
New model of deletion/duplication formation in BRCA1-deficient cells based on comprehensive multi-genotype mutational profiling
Bendegúz Szabó
17:10 – 17:30
NUP98 condensates in DNA repair regulation and oncogenesis
Jakub Cibulka
17:30 – 17:50
A genetic map of virus-perturbed DNA damage response
Ondrej Belan
18:00 – 20:00
POSTER SESSION